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Zipsor and Pregnancy

It is generally recommended that pregnant women avoid taking nonsteroidal anti-inflammatory drugs such as Zipsor (diclofenac potassium) late in pregnancy. The active ingredient in the medication is known to pass through the placenta to the fetus. If pregnancy occurs while you are taking Zipsor, be sure to talk to your healthcare provider about any potential risks.

Is Taking Zipsor During Pregnancy Safe?

Zipsor™ (diclofenac potassium) is a prescription medication used to treat pain. It is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDS may present some risks to the fetus when taken during pregnancy, although the full risks are currently unknown.
 

Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
 

Pregnancy Complications With Zipsor

As an NSAID, diclofenac (the active ingredient in Zipsor) passes through the placenta to the fetus. The most serious effects of NSAID use occur near the end of pregnancy. For this reason, it is almost always recommended that pregnant women avoid taking NSAIDs (including Zipsor) during the later part of pregnancy (from about 30 weeks on).
 
It should also be noted that women trying to become pregnant should avoid NSAIDs, since these drugs appear to interfere with the implantation process.
 
The specific risks of NSAID use during pregnancy include:
 
  • Prolonged pregnancy (since NSAIDs inhibit the prostaglandins that help stimulate labor)
  • Increased risk of miscarriage
  • Possible increased risk of birth defects (although this risk appears to be small)
  • Poor kidney function in the fetus
  • Premature closure of the ductus arteriosus (a potentially fatal heart problem) in the fetus
  • Persistent pulmonary hypertension (a very serious lung problem) in the newborn.
     
8 Frequent Pain Syndromes

Zipsor Medication Information

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