Xodol Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Xodol is combined with any of the drugs listed above.
Alcoholic Beverages
You should avoid alcohol while taking Xodol. Alcohol interacts with
hydrocodone, the narcotic component of Xodol, potentially increasing the risk of serious side effects, such as extreme drowsiness, confusion, memory loss, or difficulty breathing. Alcohol also interacts with the
acetaminophen (
Tylenol®) component of Xodol, increasing the risk of liver damage
(see Tylenol and Alcohol for more information).
Antidepressants
Combining Xodol with an
antidepressant could increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking Xodol with an antidepressant, as you may need to be monitored more closely.
Antihistamines
Many antihistamines cause significant drowsiness and can cause serious problems when used in combination with other medications that cause drowsiness, such as Xodol. Check with your healthcare provider before taking Xodol with an antihistamine, including non-prescription antihistamines in allergy, cold/cough, sleep, and motion sickness products.
Antipsychotic Medications
Combining an
antipsychotic medication with Xodol can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking Xodol with an antipsychotic medication.
Barbiturates
Combining a barbiturate with Xodol can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking these medications together.
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