Pain Channel
Topics & Medications
Related Channels

Tramadol Drug Interactions

Tramadol Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when tramadol is combined with any of the drugs listed above.
You should avoid alcohol while taking tramadol. Alcohol interacts with the medication, potentially increasing the risk of serious side effects, such as extreme drowsiness, confusion, memory loss, or difficulty breathing (see Tramadol and Alcohol for more information).
The combination of carbamazepine (a seizure medication) and tramadol should be avoided. Carbamazepine decreases the level of tramadol in the blood, making it less effective. In addition, tramadol increases the risk of seizures, especially in people with a seizure disorder (see Tramadol and Seizures).
Taking cyclobenzaprine with tramadol increases the risk of seizures. This combination should be avoided if possible, especially in people who already have seizure problems.
Combining tramadol with dextromethorphan can cause a group of symptoms called serotonin syndrome. These symptoms include:
  • Confusion
  • Hallucinations
  • A fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasms
  • Difficulty walking
  • Diarrhea.
Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be dangerous (see Tramadol and Serotonin Syndrome for more information).
Alternative Treatments for Fibromyalgia

Tramadol Medication Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2019 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.