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Side Effects of Tramadol/Acetaminophen

Common Side Effects of Tramadol/Acetaminophen

Tramadol/acetaminophen has been studied thoroughly in clinical trials. In these studies, side effects occurring in a group of people taking the drug are documented and compared to those that occur in another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common tramadol/acetaminophen side effects included:
  • Constipation -- in up to 6 percent of people
  • Drowsiness -- up to 6 percent
  • Increased sweating -- up to 4 percent
  • Diarrhea -- up to 3 percent
  • Nausea -- up to 3 percent
  • Dizziness -- up to 3 percent
  • Loss of appetite -- up to 3 percent.
  • Dry mouth -- up to 2 percent (see Ultracet and Dry Mouth)
  • Insomnia -- up to 2 percent
  • Prostate problems -- up to 2 percent.
Other side effects of tramadol/acetaminophen are possible. In studies, these side effects were reported in at least 1 percent of people (although the exact percentage was not reported) and were thought to be related to tramadol/acetaminophen. These possible tramadol/acetaminophen side effects included:
  • Weakness
  • Fatigue
  • Hot flashes
  • Headaches
  • Shakiness (tremor)
  • Nervousness
  • Abdominal pain (stomach pain)
  • Indigestion or heartburn
  • Gas
  • Vomiting
  • An unusual pleasant or happy feeling (euphoria)
  • Confusion
  • Anxiety.
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Tramadol/Acetaminophen Drug Info

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