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Drug Interactions With Tramadol/Acetaminophen

St. John's Wort
Taking tramadol/acetaminophen with St. John's wort can cause seizures or a group of dangerous symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together.
 
Trazodone (Desyrel) or Trazodone ER (Oleptro)
Taking tramadol/acetaminophen with trazodone can cause seizures or a group of dangerous symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together.
 
Tricyclic Antidepressants
Taking tramadol/acetaminophen with a tricyclic antidepressant can cause seizures or a group of dangerous symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together.
 
Triptans
Taking tramadol/acetaminophen with a triptan can cause seizures or a group of dangerous symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together.
 
Tryptophan
Taking tramadol/acetaminophen with tryptophan can cause seizures or a group of dangerous symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together.
 

Final Thoughts on Tramadol/Acetaminophen Drug Interactions

It is possible that not all drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 
Warning: 10 Hidden Sources of Lactose

Tramadol/Acetaminophen Drug Info

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