Toradol Drug Interactions

In the case of Toradol, drug interactions with the medicine may occur with a number of different medications. Examples of medications that may interact with Toradol include aspirin, ibuprofen, naproxen, lithium, and warfarin. Some of these potential interactions can increase the risk of experiencing serious side effects with Toradol. Other Toradol drug interactions can affect the way your body metabolizes the medications, and make some medicines less effective.

An Overview of Toradol Drug Interactions

• Angiotensin-converting enzyme inhibitors (ACE inhibitors), including:
   
  • Benazepril (Lotensin^®), benazepril-hydrochlorothiazide (Lotensin HCT^®), or benazepril-amlodipine (Lotrel^®)
  • Captopril (Capoten^®) or captopril-hydrochlorothiazide (Capozide^®)
  • Enalapril (Vasotec^®), enalapril-hydrochlorothiazide (Vaseretic^®), or enalapril-felodipine (Lexxel^®)
  • Fosinopril (Monopril^®) or fosinopril-hydrochlorothiazide (Monopril-HCT^®)
  • Lisinopril (Prinivil^®, Zestril^®) or lisinopril-hydrochlorothiazide (Prinzide^®, Zestoretic^®)
  • Quinapril (Accupril^®) or quinapril-hydrochlorothiazide (Accuretic^®, Quinaretic™)
  • Ramipril (Altace^®)

• Angiotensin II receptor blockers (ARBs), such as:

• • Azilsartan (Edarbi™) or azilsartan/chlorthalidone (Edarbyclor™)
  • Candesartan (Atacand^®) or candesartan-hydrochlorothiazide (Atacand HCT^®)
  • Eposartan (Teveten^®) or eposartan-hydrochlorothiazide (Teveten^® HCT)
  • Irbesartan (Avapro^®) or irbesartan-hydrochlorothiazide (Avalide^®)
  • Losartan (Cozaar^®) or losartan-hydrochlorothiazide (Hyzaar^®)
  • Olmesartan (Benicar^®), olmesartan-hydrochlorothiazide (Benicar HCT^®), or amlodipine and olmesartan (AZOR™)
  • Telmisartan (Micardis^®) or telmisartan-hydrochlorothiazide (Micardis^® HCT)
  • Valsartan (Diovan^®) or valsartan-hydrochlorothiazide (Diovan HCT^®)

• Beta blockers, such as:
   
  • Acebutolol (Sectral^®)
  • Atenolol (Tenormin^®)
  • Betaxolol (Kerlone^®)
  • Bisoprolol (Zebeta^®)
  • Carvedilol (Coreg^®, Coreg CR^®)
  • Esmolol (Brevibloc^®)
  • Labetalol (Trandate^®)
  • Metoprolol (Lopressor^®, Toprol-XL^®)
  • Nadolol (Corgard^®)
  • Nebivolol (Bystolic^®)
  • Penbutolol (Levatol^®)
  • Propranolol (Inderal^®, Inderal^® LA, InnoPran XL™)
  • Sotalol (Betapace^®)
  • Timolol

• Bile acid sequestrant cholesterol medications, including:
   
  • Cholestyramine (Prevalite^®, Questran^®, Questran^® Light)
  • Colesevelam (WelChol^®)
  • Colestipol (Colestid^®)

• Corticosteroids, including (but not limited to):
   
  • Betamethasone (Celestone^®)
  • Cortisone
  • Dexamethasone (Decadron^®)
  • Fludrocortisone (Florinef^®)
  • Hydrocortisone (Cortef^®)
  • Methylprednisolone (Depo-Medrol^®, Medrol^®)
  • Prednisolone (Orapred^®, Pediapred^®)
  • Prednisone
  • Triamcinolone (Kenalog^®, Aristospan^®)

• Cyclosporine (Gengraf^®, Neoral^®, Sandimmune^®)
• Digoxin (Digitek^®, Lanoxin^®)
• Diuretics, such as:
   
  • Amiloride (Midamor^®) or amiloride-HCTZ (Moduretic^®)
  • Bumetanide (Bumex^®)
  • Chlorothiazide (Diuril^®)
  • Chlorthalidone (Thalitone^®)
  • Ethacrynic acid (Edecrin^®)
  • Furosemide (Lasix^®)
  • Hydrochlorothiazide (Esidrix^®, HydroDIURIL^®, Microzide^®, Oretic^®)
  • Metolazone (Zaroxolyn^®)
  • Spironolactone (Aldactone^®) or spironolactone-HCTZ (Aldactazide^®)
  • Torsemide (Demadex^®)
  • Triamterene (Dyrenium^®) or triamterene/HCTZ (Dyazide^®, Maxzide^®)

• Lithium (Eskalith^®, Lithobid^®)
• Medications that "thin" the blood or otherwise increase bleeding risk (such as anticoagulant and antiplatelet drugs), such as:
   
  • Antithrombin (ATryn^®, Thrombate III^®)
  • Apixaban (Eliquis^®)
  • Argatroban
  • Aspirin (Bayer^® and others)
  • Bivalirudin (Angiomax^®)
  • Cilostazol (Pletal^®)
  • Clopidogrel (Plavix^®)
  • Dabigatran (Pradaxa^®)
  • Dipyridamole (Persantine^®)
  • Drotrecogin alfa (Xigris^®)
  • Eptifibatide (Integrilin^®)
  • Fondaparinux (Arixtra^®)
  • Heparin or heparin-like products, including dalteparin (Fragmin^®), enoxaparin (Lovenox^®), or tinzaparin (Innohep^®)
  • Lepirudin (Refludan^®)
  • Other nonsteroidal anti-inflammatory drugs (NSAIDs), such as:

• • • Celecoxib (Celebrex^®)
    • Diclofenac (Cambia™, Cataflam^®, Flector^®, Solaraze^® Gel, Voltaren^®, Voltaren^® Gel, Voltaren^®-XR, Voltaren Ophthalmic^®, Zipsor™)
    • Etodolac (Lodine^®, Lodine^® XL)
    • Ibuprofen (Motrin^®, Advil^®, Nuprin^®)
    • Indomethacin (Indocin^®, Indocin SR^®)
    • Ketoprofen (Orudis^®, Actron^®, Oruvail^®)
    • Meloxicam (Mobic^®)
    • Nabumetone (Relafen^®)
    • Naproxen (Naprosyn^®) or naproxen sodium (Aleve^®, Anaprox^®, Naprelan^®)
    • Oxaprozin (Daypro^®)
    • Piroxicam (Feldene^®)
    • Others (see List of NSAIDs for a more complete list of these medications)

• • Pentoxifylline (Trental^®)
  • Prasugrel (Effient^®)
  • Rivaroxaban (Xarelto^®)
  • Thrombolytics, such as:

• • • Alteplase (Activase^®)
    • Reteplase (Retavase^®)
    • Streptokinase (Streptase^®)
    • Tenecteplase (TNKase^®)

• • Ticagrelor (Brilinta^®)
  • Ticlopidine (Ticlid^®)
  • Tirofiban (Aggrastat^®)
  • Warfarin (Coumadin^®, Jantoven^®)

• Methotrexate (Rheumatrex^®, Trexall^®)
• Probenecid
• SSRI or SNRI medications, including:
   
  • Citalopram (Celexa^®)
  • Duloxetine (Cymbalta^®)
  • Desvenlafaxine (Pristiq^®)
  • Escitalopram (Lexapro^®)
  • Fluoxetine (Prozac^®, Sarafem^®, Selfemra™)
  • Fluvoxamine (Luvox^®, Luvox^® CR)
  • Levomilnacipran (Fetzima™)
  • Milnacipran (Savella™)
  • Paroxetine (Paxil^®, Paxil CR^®, Pexeva^®, Brisdelle™)
  • Sertraline (Zoloft^®)
  • Venlafaxine (Effexor^®, Effexor XR^®)

• Seizure medicines, such as:
   
  • Phenytoin (Dilantin^®, Phenytek^®)
  • Carbamazepine (Carbatrol^®, Epitol^®, Tegretol^®, Tegretol^®-XR, Equetro™)

• Psychoactive drugs, such as:
   
  • Fluoxetine (Prozac^®)
  • Thiothixene (Navane^®)
  • Alprazolam (Xanax^®, Xanax XR^®, Niravam™).

• Dong quai
• Feverfew
• Garlic
• Ginger
• Ginkgo biloba
• Ginseng
• St. John's wort
• Fish oil supplements.