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Side Effects of Tapentadol ER

Common Side Effects

Tapentadol ER has been studied extensively in clinical trials. In these studies, one group of people received the real medication, while another group was given a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
 
In these studies, the most common tapentadol ER side effects included:
 
  • Nausea -- in up to 27 percent of people
  • Constipation -- up to 17 percent
  • Dizziness -- up to 18 percent
  • Headaches -- up to 15 percent
  • Drowsiness -- up to 14 percent
  • Fatigue -- up to 9 percent
  • Vomiting -- up to 12 percent
  • Itching -- up to 8 percent
  • Diarrhea -- up to 7 percent
  • Dry mouth -- up to 7 percent
  • Decreased appetite -- up to 6 percent.
  •   
Other common reactions, occurring in 1 to 5 percent of people, included but were not limited to:
 
 

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
 
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking tapentadol ER. Also, let your healthcare provider know if you develop something that "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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Tapentadol ER Medication Information

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