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Talacen Warnings and Precautions

Specific Precautions and Warnings for Talacen

Some warnings and precautions to be aware of prior to taking this drug include the following:
  • Talacen contains a sulfite, which may cause serious allergic-type reactions or asthma attacks in people who are sensitive to sulfites. Although an allergy to sulfites is generally considered to be rare, it may be more common in people with asthma. A sulfite allergy is not the same as a "sulfa" allergy (an allergy to sulfonamide medications).
  • Talacen contains acetaminophen, which has been reported to cause serious allergic reactions. Let your healthcare provider know immediately if you develop signs of an allergic reaction, such as:
    • A rash
    • Hives
    • Itching
    • Problems breathing
    • Swelling of the mouth, face, or throat
    • Vomiting.
  • Talacen should only be taken by mouth. Do not try to dissolve and inject the medication, either alone or with other substances. Injecting this medication can lead to serious and potentially fatal reactions.
  • Talacen can make you extremely drowsy and dizzy, which could affect your reflexes and reaction times. Do not drive, operate heavy machinery, or perform any activities requiring alertness if you experience these side effects.
  • Your body may become used to this medication if you take it for more than a few weeks, and stopping it suddenly could cause withdrawal symptoms. Instead, your healthcare provider may need to slowly reduce your dosage to help minimize withdrawal symptoms. Let your healthcare provider know if you develop symptoms of withdrawal while you are being taken off this medicine. Possible withdrawal symptoms may include:
    • Abdominal (stomach) cramps
    • Nausea
    • Vomiting
    • Fever
    • Chills
    • Runny nose
    • Restlessness
    • Anxiety
    • Watery eyes.
  • Talacen can cause respiratory depression, which is extremely slow, irregular, or shallow breathing. Although generally rare with Talacen use, respiratory depression is more likely to occur in people who already have breathing problems, older adults, and people who are taking other medicines that slow down breathing.
  • Talacen is a narcotic medication, and like other narcotics, has the potential to become habit-forming. People with a history of drug or alcohol abuse may have a higher chance of becoming addicted to Talacen. Take this medication exactly as prescribed; do not take more of it, take it more often than recommended, or use it for a non-medical purpose. Let your healthcare provider know if you may be developing a problem with Talacen abuse.
  • Like other narcotics, Talacen may be dangerous for people with high pressure around the brain, such as those with head injuries. It should be used with extreme caution in such people, and only if absolutely necessary.
  • Do not drink alcohol or take other opioids or other medicines that make you drowsy while using Talacen without your healthcare provider's approval. Doing so may increase the risk for serious side effects, including extreme drowsiness, confusion, memory loss, or abnormally slow breathing. In addition, Talacen may block the actions of certain other opioids, potentially making them less effective or causing withdrawal symptoms.
  • There have been reports of hallucinations (seeing or hearing things that are not real), disorientation, and confusion in people taking Talacen. People who develop side effects such as these should be carefully monitored until the symptoms improve. In most cases, the symptoms resolve on their own within a few hours.
  • There have been reports of seizures occurring in people taking Talacen. Make sure your healthcare provider knows if you have a seizure disorder before taking this medication.
  • Talacen should be used cautiously in people with porphyria, a rare genetic condition associated with the abnormal production of heme (a substance found throughout the body, especially in the blood and bone marrow), as it may trigger an acute porphyria attack.
  • This medication can increase blood pressure, and should be used cautiously in people for whom an increase in blood pressure would be particularly dangerous.
  • People with liver disease may be more susceptible to Talacen side effects. In addition, Talacen contains acetaminophen, which can cause liver damage. Talk to your healthcare provider before taking Talacen if you have liver disease.  
  • It is important to make sure your healthcare provider knows your complete medical history before taking this medicine. Talacen should be used with caution in people with the following medical issues:
    • Kidney disease
    • An underactive thyroid
    • Adrenal gland problems
    • An enlarged prostate
    • Certain abdominal (stomach) or intestinal problems
    • Gallbladder disease
    • Conditions of the pancreas
    • People who are intoxicated on alcohol.
  • Talacen passes through breast milk. Therefore, if you are breastfeeding or plan to start, you should discuss this with your healthcare provider prior to taking the drug (see Talacen and Breastfeeding).
  • Talacen is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Talacen and Pregnancy).
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