Sumatriptan/Naproxen Sodium Dosage

The standard sumatriptan/naproxen sodium dosage for treating migraine headaches is one tablet, taken as soon as possible once a migraine starts. It is not known whether taking a second dose (if the first does not work adequately) is effective. You should not take more than two sumatriptan/naproxen sodium doses in a 24-hour period.

 

Sumatriptan/Naproxen Sodium Dosage: An Introduction

There is only one standard recommended dose for sumatriptan/naproxen sodium (Treximet™). As always, do not adjust your sumatriptan/naproxen sodium dose unless your healthcare provider specifically instructs you to do so.
 

Sumatriptan/Naproxen Sodium Dosing for Migraines

The recommended sumatriptan/naproxen sodium dose for treating a migraine is one tablet (85 mg of sumatriptan and 500 mg of naproxen sodium). Using a second dose if the first does not work adequately has not been studied. Do not take a second dose within two hours of the first, and do not take more than two tablets in 24 hours.
 

General Information on Dosing With Sumatriptan/Naproxen Sodium

Some considerations for people using sumatriptan/naproxen sodium include the following:
 
  • Sumatriptan/naproxen sodium comes in tablet form. It is taken by mouth as soon as possible once a migraine starts.
     
  • Swallow sumatriptan/naproxen sodium tablets whole with a drink of water or other fluids.
     
  • Sumatriptan/naproxen sodium can be taken with or without food. Because one of the components of the medication (naproxen sodium) can be irritating to the stomach, it may be a good idea to take sumatriptan/naproxen sodium with a little food (although this may not be possible due to nausea from the migraine).
     
  • Do not take two doses of sumatriptan/naproxen sodium within two hours of each other.
     
  • For sumatriptan/naproxen sodium to work properly, it must be taken as prescribed. The medication will not work if you stop taking it.
     
  • If you are unsure about anything related to your sumatriptan/naproxen sodium dosage, please talk to your doctor, nurse, or pharmacist.
     
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;