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Side Effects of Sumatriptan/Naproxen Sodium

Common side effects of sumatriptan/naproxen sodium may include indigestion or heartburn, chest pain, drowsiness, and nausea. Although most side effects are minor, some are potentially serious and require immediate medical attention, such as bloody diarrhea, vision changes, or high blood pressure. Rare but possible sumatriptan/naproxen sodium side effects (occurring in less than 1 percent of people taking the drug) include cataracts, diabetes, and hot flashes.

An Introduction to Sumatriptan/Naproxen Sodium Side Effects

As with any medicine, sumatriptan/naproxen sodium (Treximet™) can cause side effects. However, not everyone who takes sumatriptan/naproxen sodium will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with sumatriptan/naproxen sodium. Your healthcare provider can discuss a more complete list of sumatriptan/naproxen sodium side effects with you.)

Serious Side Effects Seen With Sumatriptan/Naproxen Sodium

There are a number of side effects with sumatriptan/naproxen sodium that you should report to your healthcare provider. These include, but are not limited to:
  • Severe chest pain or tightness
  • Shortness of breath
  • Sudden severe abdominal pain (stomach pain)
  • Bloody diarrhea
  • Changes in vision, including loss of vision
  • Seizures
  • Worsening of asthma
  • High blood pressure (hypertension)
  • Rapid weight gain, swelling, or water retention
  • Signs of bleeding in the digestive tract, such as dark, tarry stools or vomiting of blood
  • Signs of an allergic reaction, including unexplained skin rashes, itching, hives, wheezing or shortness of breath, and unexplained swelling.
Taking sumatriptan/naproxen sodium with certain antidepressants can increase your risk of a group of dangerous symptoms called serotonin syndrome. Contact your healthcare provider immediately if you have any of the following symptoms of serotonin syndrome:
  • Confusion
  • Seeing or hearing things that are not really there (hallucinations)
  • Fast heartbeat (tachycardia)
  • Fainting
  • Fever
  • Sweating
  • Muscle spasms
  • Difficulty walking
  • Diarrhea.
8 Frequent Pain Syndromes

Info on Sumatriptan/Naproxen Sodium

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