Make sure you are aware of the precautions and warnings with sumatriptan/naproxen sodium before starting the drug. Since the medication can worsen certain medical conditions, you should tell your healthcare provider about any existing conditions you have, such as high blood pressure or congestive heart failure. You should avoid taking sumatriptan/naproxen sodium altogether if you have liver problems, hemiplegic or basilar migraines, or angina.

• Heart problems of any kind, especially a history of heart disease, angina, an irregular heart rhythm, or a heart attack
• A history of stroke, transient ischemic attack (TIA or "mini-stroke"), or other bleeding in the brain (such as a subarachnoid hemorrhage)
• Congestive heart failure (CHF)
• High blood pressure (hypertension)
• High cholesterol
• Diabetes
• Certain blood vessel conditions, such as peripheral vascular disease, ischemic bowel disease, or Raynaud's phenomenon
• Kidney problems, including kidney failure (renal failure)
• Liver problems, including liver failure or cirrhosis
• A history of seizures or epilepsy
• Asthma
• Any allergies, including allergies to foods, dyes, or preservatives.
   

• Are pregnant or thinking of becoming pregnant
• Are breastfeeding
• Smoke
• Have a family history of heart disease.