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Subutex Drug Interactions

Several drugs may cause negative interactions with Subutex. Complications may occur if the narcotic is taken with products such as benzodiazepines, medications that cause drowsiness, or alcohol. Some of these reactions could increase your risk for side effects (such as drowsiness, confusion, or difficulty breathing), while others can lead to more dangerous and even fatal problems.

An Overview of Interactions With Subutex

Subutex® (sublingual buprenorphine) may react with a number of other medications. Some of the drugs that may lead to interactions with Subutex include but are not limited to:
  • Alcohol
  • Benzodiazepines, such as:
  • CYP 3A4 inducer medications, such as:
  • CYP 3A4 inhibitor medications, such as:
  • Medications that cause drowsiness, such as:
  • Monoamine oxidase inhibitors (MAOIs), such as:


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Subutex Medication Information

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