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Subsys Drug Interactions

Subsys Drug Interactions Explained

The following sections explain in detail the potentially negative reactions that can occur when Subsys is combined with any of the drugs listed above.
 
Alcohol
Consuming alcohol while using Subsys could potentially increase your risk for serious side effects, including extreme drowsiness, confusion, or difficulty breathing. You should not drink alcohol while using this medication.
 
Alvimopan
Subsys may increase the risk for serious alvimopan side effects. Do not take alvimopan if you have used Subsys in the past seven days.
 
Amphetamines
Combining amphetamines with Subsys may increase the pain-relieving effects of Subsys. Your healthcare provider may choose to monitor your response to Subsys if you take these medications together. You may need a lower Subsys dose.
 
Beta Blockers
Using Subsys with a beta blocker may lower your heart rate and blood pressure, potentially to unsafe levels. If you take these medications together, your healthcare provider may need to monitor your blood pressure and heart rate more closely.
 
Calcium Channel Blockers
Using Subsys with certain calcium channel blockers may lower your heart rate and blood pressure, potentially to unsafe levels. Your healthcare provider may need to monitor your blood pressure and heart rate more closely if you take these medications together.
 
CYP 3A4 Inducer Medications
The liver breaks down Subsys using enzymes known as CYP 3A4 enzymes. Medications known as CYP 3A4 inducers can increase the activity of these enzymes. Combining Subsys with one of these CYP 3A4 inducers may decrease the level of Subsys in your body, making it less effective. Your healthcare provider may need to monitor you more closely to make sure your pain is adequately controlled if you use Subsys with a CYP 3A4 inducer.
5 Common Pain Medication Fears

Subsys Medication Information

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