Suboxone Drug Interactions

Several products can cause potentially dangerous drug interactions with Suboxone, including alcohol, benzodiazepines, and sleep medications. These reactions could increase your risk for serious side effects, such as extreme drowsiness, confusion, and difficulty breathing. To avoid any complications, make sure your healthcare provider is aware of any other medications you are taking, including nonprescription drugs and herbal supplements.

An Overview of Interactions With Suboxone

Suboxone® (buprenorphine and naloxone) may potentially react with a number of other medications. Some of the drugs that may lead to interactions with Suboxone include but are not limited to:
 
  • Alcohol
  • Benzodiazepines, such as:
 
 
  • CYP 3A4 inducer medications, such as:
 
 
  • CYP 3A4 inhibitor medications, such as:
 
 
  • Medications that cause drowsiness, such as:
 
 
  • Monoamine oxidase inhibitors (MAOIs), such as:
 
 
  • Other opioids, such as:
 
 
Suboxone Drug Interactions Article Continues on Next Page >
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD
 
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