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How Long Does Suboxone Stay in Your System?

Suboxone® (buprenorphine and naloxone) is a medicine prescribed for the treatment of opioid dependence. It comes in the form of a tablet or a film that is dissolved under the tongue.
How long does Suboxone stay in your system? Suboxone lasts long enough that you only have to use it once a day. Based on the buprenorphine content, this medicine has a half-life of 24 to 42 hours. This means that it takes 24 to 42 hours for the level of buprenorphine to drop by 50 percent in your blood. Therefore, it may take several days, or even a week or longer, for this drug to be mostly out of your system.
(Click Suboxone for more information on how long this drug stays in your system. This Web selection also describes how this medication works, when and how to use it, and why it is not suitable for certain people.)
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