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Sprix Drug Interactions

Sprix Drug Interactions Explained

The following sections explain in detail the potential problems that can occur when Sprix is combined with any of the drugs mentioned above.
 
ACE Inhibitors
Using Sprix in combination with ACE inhibitors may increase the risk of kidney damage. In addition, ACE inhibitors may not lower your blood pressure as well when taken with Sprix. Your healthcare provider may choose to monitor your blood pressure and your kidney function if you take these medications together.
 
Angiotensin II Receptor Blockers (ARBs)
Using Sprix in combination with ARBs may increase the risk of kidney damage. In addition, ARBs may not lower your blood pressure as well when taken with Sprix. Your healthcare provider may choose to monitor your blood pressure and your kidney function if you take these medications together.
 
Corticosteroids
Using corticosteroids with Sprix can increase the risk of bleeding. Your healthcare provider may choose to monitor you more closely or adjust your dose of these drugs.
 
Cyclosporine
Sprix may increase the level of cyclosporine in the blood, increasing the risk of serious cyclosporine side effects. In addition, this combination may increase the risk of kidney damage. Check with your healthcare provider before taking these medications together.
 
Digoxin
Sprix may increase the level of digoxin in your bloodstream, increasing the risk of dangerous digoxin side effects. If you are taking digoxin, check with your healthcare provider before starting or stopping Sprix.
 
Diuretics
Sprix can make diuretics less effective. If you use these medications together, your healthcare provider should monitor your kidney function, as well as how well your diuretic is working. You may need higher doses of the diuretic.
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Sprix Medication Information

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