Savella Overdose

Taking too much Savella (milnacipran) can be dangerous and requires immediate medical attention. Potential overdose symptoms include breathing problems, high blood pressure, and drowsiness. An overdose may also lead to cardiac arrest, coma, or loss of life. Treatment involves "pumping the stomach," taking certain medications, or treating the symptoms that occur as a result of the Savella overdose.

Can You Take Too Much Savella?

Savella™ (milnacipran hydrochloride) is a prescription fibromyalgia medication. As with any medication, it is possible to take too much Savella. The specific effects of an overdose can vary, depending on a number of factors, including the Savella dosage and whether it was taken with any other medications or substances.
 
Seek immediate medical attention if you or someone else may have overdosed on Savella, as it can be dangerous.
 

Symptoms of an Overdose With Savella

A Savella overdose may cause the following symptoms:
 
  • High blood pressure (hypertension)
  • Cardiac arrest
  • Breathing problems
  • Drowsiness
  • Coma
  • Confusion
  • Dizziness
  • High liver enzymes (found using a blood test)
  • Loss of life.
     
Although loss of life was more common when Savella was taken with other drugs, fatalities have been reported with Savella use alone as well.
 
An overdose with Savella can also cause serotonin syndrome. Symptoms of this condition include:
 
  • Confusion or other mental changes
  • A rapid heart rate
  • Nausea
  • Vomiting
  • Diarrhea
  • Hallucinations
  • Blood pressure changes
  • Overactive reflexes
  • Fever
  • Shivering
  • Shakiness
  • Agitation
  • Sweating
  • Seizures
  • Coma.
      
(Savella Overdose Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
Other Articles in This eMedTV Presentation