Ryzolt Drug Interactions

Several medications can cause potentially dangerous drug interactions with Ryzolt, including sleep medications, digoxin, and triptans. Drug interactions can lead to many problems in the body. For example, problems could occur that may increase your risk of a dangerous condition known as serotonin syndrome. Contact your healthcare provider right away if you develop any symptoms of serotonin syndrome, such as confusion, hallucinations, fever, sweating, muscle spasms, difficulty walking, or diarrhea.

Ryzolt Medication Information

Ryzolt Drug Interactions: An Overview

Ryzolt^™ (tramadol ER) is a prescription pain medication that can potentially interact with a number of other medications, particularly other medications that cause sedation or affect serotonin levels (an important neurotransmitter). Some of the medicines that may lead to drug interactions with Ryzolt include, but are not limited to:

Alcoholic beverages
Carbamazepine (Carbatrol^®, Epitol^®, Equetro^®, Tegretol^®)
Cyclobenzaprine (Flexeril^®, Amrix^®)
Dextromethorphan (a common active ingredient in cough medications)
Digoxin (Digitek^®, Lanoxin^®)
Linezolid (Zyvox^®)
Other medications that cause drowsiness, including, but not limited to:

Antipsychotic medications
Anxiety medications
Most antidepressants
Narcotic pain relievers
Sleep medications
Some antihistamines

Promethazine (Phenadoz^™, Phenergan^®, Promethegan^™)
Quinidine
Sibutramine (Meridia^®)
St. John's wort
Triptans, including:

Tryptophan
Warfarin (Coumadin^®, Jantoven^®).

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