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Ryzolt Drug Interactions

Linezolid
Taking Ryzolt with linezolid can cause a group of symptoms called serotonin syndrome. These symptoms include confusion, hallucinations, a fast heartbeat, feeling faint, fever, sweating, muscle spasms, difficulty walking, and diarrhea. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous (see Tramadol and Serotonin Syndrome for more information).
 
Medications That Cause Drowsiness
Combining Ryzolt with any other medications that cause drowsiness can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking Ryzolt with such medications. Additionally, combining Ryzolt with some of these medications may increase the risk of seizures or serotonin syndrome (see Tramadol and Serotonin Syndrome and Tramadol and Seizures for a list of medications that can cause these problems when taken with Ryzolt).
 
Promethazine
Combining promethazine and Ryzolt can increase the risk of seizures or other side effects of Ryzolt. Check with your healthcare provider before combining these medications.
 
Quinidine
The liver metabolizes Ryzolt into a substance known as M1 that is responsible for much of the pain-relieving properties of Ryzolt. Quinidine interferes with the liver's ability to metabolize Ryzolt into M1, which might possibly make the medication less effective.
 
Sibutramine
Taking Ryzolt with sibutramine can cause seizures or a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be very dangerous.
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Ryzolt Medication Information

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