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Rybix ODT Drug Interactions

Quinidine
The liver metabolizes Rybix ODT into a substance known as M1 that is responsible for much of the pain-relieving properties of Rybix ODT. Quinidine interferes with the liver's ability to metabolize Rybix ODT into M1, which might make the medication less effective.
 
Sibutramine
Taking Rybix ODT with sibutramine can cause seizures or a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be dangerous.
 
St. John's Wort
Combining Rybix ODT with St. John's wort can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be dangerous.
 
Triptans
Combining Rybix ODT with a triptan can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be dangerous.
 
Tryptophan
Taking Rybix ODT with tryptophan can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be dangerous.
 
Warfarin
There have been rare reports of a possible interaction between warfarin and Rybix ODT. This interaction might increase your risk of bleeding. Check with your healthcare provider before combining these drugs; you may need to be monitored more closely.
 
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Rybix ODT Medication Information

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