Relafen Drug Interactions

There are many potential Relafen drug interactions to be aware of. For example, Relafen can interact with other nonsteroidal anti-inflammatory drugs like ibuprofen and oxaprozin -- as well as with corticosteroids and herbal or nutritional supplements -- to increase your risk of bleeding. Relafen drug interactions can also reduce the effectiveness of ACE inhibitors and diuretics. Kidney damage and an increased risk of stomach ulcers can also result from drug interactions with Relafen.

 

Relafen Drug Interactions: An Introduction

Relafen® (nabumetone) can potentially interact with a number of medicines. Some of these Relafen drug interactions include:
 

 

Several herbal and nutritional supplements can also interact with Relafen and may increase the risk of bleeding. Examples of these include, but are not limited to:
 
Warfarin (Coumadin, Jantoven)
If you are taking other blood thinners, such as warfarin, while taking Relafen, your body may metabolize them differently than intended. You healthcare provider may choose to monitor your INR and prothrombin time more frequently and adjust accordingly. INR and prothrombin time are tests used to measure how well your blood is clotting.
(Relafen Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;