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Pregabalin Dosing
A healthcare provider will consider several factors when prescribing your dose of pregabalin, such as other drugs you may be taking. For people with postherpetic neuralgia, dosing usually starts at 75 mg twice daily or 50 mg three times daily. The suggested starting dosage for those with fibromyalgia is 75 mg twice daily.
The dose of pregabalin (Lyrica®) that your healthcare provider recommends will vary depending on a number of factors, including:
- The medical condition being treated
- Other medications you may be taking
- Other medical conditions you may have.
As always, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
Diabetic Peripheral Neuropathy
The recommended starting pregabalin dose for treating nerve pain due to diabetic neuropathy is 50 mg three times daily. Your healthcare provider may increase your dosage (up to a maximum of pregabalin 100 mg three times daily) within a week if necessary to control your pain -- and if you tolerate pregabalin well. If you have kidney disease, you may need a lower dosage.
Epileptic Seizures
The recommended starting pregabalin dose for controlling partial seizures in people with epilepsy is 75 mg twice daily or 50 mg three times daily. If necessary to control your seizures, your healthcare provider may increase your dosage, up to a maximum of pregabalin 200 mg three times daily.
It is important to understand that pregabalin is approved to treat seizures only when used in combination with other seizure medications. If you have kidney disease, you may need a lower pregabalin dose.
Fibromyalgia
The recommended starting pregabalin dose for fibromyalgia treatment is 75 mg twice daily. If necessary, your healthcare provider may increase your dose, up to pregabalin 225 mg twice daily. If you have kidney disease, you may need a lower dosage.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD