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Pregabalin Dosing

Postherpetic Neuralgia
For treating postherpetic neuralgia (chronic nerve pain following an episode of shingles), the recommended starting dose is pregabalin 75 mg twice daily or 50 mg three times day. If necessary to control your pain, your healthcare provider may increase your dose up to pregabalin 150 mg twice daily or 100 mg three times daily within the first week of treatment.
 
If you are still experiencing pain after two to four weeks (and if you are tolerating pregabalin well), your healthcare provider may increase your dosing even further, up to 300 mg twice daily or 200 mg three times daily. If you have kidney disease, you may need a lower pregabalin dose.
 
Spinal Cord Injury
For treating nerve pain due to a spinal cord injury, the recommended starting dose is 75 mg, taken twice daily. If necessary to control your pain, your healthcare provider may increase your dose up to pregabalin 150 mg twice daily within the first week of treatment. If you are still experiencing pain after two to three weeks (and you are tolerating the drug well), your healthcare provider may increase your dose even further, up to pregabalin 300 mg twice daily. If you have kidney disease, you may need a lower amount.
  

General Information on Taking Pregabalin

Some considerations for people taking pregabalin include:
 
  • Pregabalin comes in capsule and liquid form. It is taken by mouth, usually two or three times daily.
     
  • Pregabalin can be taken with or without food. If pregabalin upsets your stomach, try taking it with food.
     
  • Pregabalin should be taken at the same times each day to maintain even levels of the drug in your blood.
     
  • For the medication to work properly, it must be taken as prescribed. It will not work if you stop taking it.
     
  • If you are unsure about anything related to your dosage or pregabalin dosing in general, talk with your healthcare provider, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider (see Lyrica Withdrawal).
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