Percocet Drug Interactions

Alcohol, antihistamines, and barbiturates are just a few of the substances that can cause Percocet drug interactions. These interactions can increase your risk of serious side effects, including memory loss, confusion, and difficulty breathing. To reduce your risk of drug interactions with Percocet, tell your healthcare provider about any other medications you are taking, including non-prescription medications.

Percocet Drug Information

An Overview of Percocet Drug Interactions

Percocet^® (oxycodone/APAP) can potentially interact with a number of other medications. Some of the medicines that may lead to Percocet drug interactions include:

Alcohol
Antidepressants
Antihistamines
Barbiturates, such as:
- Amobarbital (Amytal^®)
- Butalbital (Fioricet^®, Fiorinal^®)
- Pentobarbital (Nembutal^®)
- Phenobarbital (Luminal^®)
- Secobarbital (Seconal^®)

Benzodiazepines, such as:
- Alprazolam (Xanax^®, Xanax XR^®)
- Chlordiazepoxide (Librium^®, Limbitrol^®, Librax^®)
- Clonazepam (Klonopin^®)
- Clorazepate (Tranxene^®)
- Diazepam (Valium^®)
- Estazolam (ProSom^®)
- Flurazepam (Dalmane^®)
- Lorazepam (Ativan^®)
- Idazolam (Versed^®)
- Temazepam (Restoril^®)
- Triazolam (Halcion^®)

Lamotrigine (Lamictal^®)
Other acetaminophen products, including many prescription and non-prescription pain killers and cold or cough products
Other narcotics or opiates, such as morphine (MS Contin^®, MSIR^®) or hydrocodone/APAP (Lortab^®, Vicodin^®, and others)
Phenothiazine medications, including:
- Chlorpromazine (Thorazine^®)
- Perphenazine (Trilafon^®)
- Prochlorperazine (Compazine^®, Compro^®)
- Thioridazine (Mellaril^®)
- Trifluoperazine (Stelazine^®)

Sleep medications
Zidovudine (Retrovir^®).

(Percocet Drug Interactions Continued: Page 2)