Percocet and Pregnancy

Little research has been done on Percocet and pregnancy. However, the two main components of it have been studied in pregnant women. Acetaminophen is considered fairly safe during pregnancy, and oxycodone doesn't appear to increase the risk of birth defects. The main concern is that, since the drug is a narcotic, using Percocet during the end of pregnancy could lead to narcotic withdrawal in the infant after delivery.

Can I Use Percocet During Pregnancy?

Percocet® (oxycodone/APAP) is a prescription pain medication. Based on animal studies and limited human studies, the drug may not be safe for use during pregnancy.
 

Percocet and Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been adequately studied in pregnant humans but that do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
 
Although Percocet has not been studied in pregnant humans or animals, the individual components of the drug (oxycodone and acetaminophen) have been studied. Usually, acetaminophen is considered fairly safe for use during pregnancy (see Tylenol and Pregnancy).
 
When given to pregnant animals, oxycodone did not seem to increase the risk of birth defects or other problems. Limited human research also suggests that oxycodone does not seem to cause birth defects in humans. However, oxycodone is a narcotic, and using this drug during the end of a pregnancy may cause narcotic withdrawal symptoms in the infant after delivery. Such symptoms may include:
 
  • Irritability and excessive crying
  • Shakiness (tremors)
  • Hyperactive reflexes
  • Fast breathing
  • Increased stools
  • Sneezing
  • Yawning
  • Vomiting
  • Fever.
     
However, pregnancy Category C medicines, including Percocet, may be given to a pregnant woman if her healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.
 
 
8 Frequent Pain Syndromes

Percocet Drug Information

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