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Pentazocine Maximum Safe Dose

Pentazocine lactate (Talwin®) is a prescription medication used before surgery or anesthesia, or to treat moderate-to-severe pain. It comes as a liquid that is given as an injection every three to four hours. The dose you receive will depend on your age, weight, and how you respond to the drug, among other factors.
Pentazocine can be given as an injection into a vein (an intravenous, or IV, injection), a muscle (an intramuscular, or IM, injection), or beneath the skin (a subcutaneous, or SC, injection). However, it should only be given as an SC injection if absolutely necessary, as these injections can cause severe skin damage.
Single doses of pentazocine should not exceed 30 mg if given by IV, or 60 mg if given by IM injection. In addition, the maximum total daily doses should not exceed 360 mg, regardless of how the medication is injected.  
(To learn more about this medicine, click Pentazocine Dosage. This full-length article discusses how your dose is calculated, and what the maximum amount is for using this drug safely.)
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