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OxyContin Drug Interactions

Barbiturates
Combining a barbiturate with OxyContin can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking OxyContin with a barbiturate.
 
Benzodiazepines
Taking OxyContin in combination with a benzodiazepine might increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking OxyContin with any benzodiazepines.
 
Monoamine Oxidase Inhibitors (MAOIs)
Combining OxyContin with an MAOI can cause serious reactions. Do not use OxyContin and an MAOI within 14 days of each other.
 
Muscle Relaxants
Taking OxyContin with a muscle relaxant may increase the risk of side effects due to both medications. Check with your healthcare provider before combining OxyContin with a muscle relaxant.
 
Other Narcotics or Opioids
Use extreme caution when combining OxyContin with other narcotics or opioids, as serious side effects could occur. You should only use these medications together with your healthcare provider's approval and supervision.
 
Sleep Medications
OxyContin can cause significant drowsiness, and combining it with a sleep medication could lead to dangerous effects. In general, OxyContin should not be used in combination with sleep medications, unless your healthcare provider specifically recommends that you do so.
 

Final Thoughts on OxyContin Drug Interactions

It is possible that not all drug interactions with OxyContin were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 
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OxyContin Medication Information

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