You should talk with your healthcare provider prior to taking oxycodone/APAP if you have:
- A history of drug or alcohol dependence
- Gallbladder or pancreas disease
- Liver disease, such as cirrhosis, liver failure, or hepatitis
- Kidney disease, such as kidney failure (renal failure)
- A head injury or high intercranial pressure
- Severe abdominal (stomach) pain
- Addison's disease
- Low blood pressure (hypotension)
- An enlarged prostate (benign prostatic hypertrophy, or BPH)
- Lung disease of any sort
- Seizures or epilepsy
- Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Oxycodone/APAP and Pregnancy)
- Breastfeeding (see Oxycodone/APAP and Breastfeeding).
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Oxycodone/APAP to learn more, including information on who should not take the drug.)