Oxycodone/APAP Overdose

The effects of an oxycodone/APAP overdose can be quite serious, as both components of the drug can be dangerous if too much is taken. Possible symptoms may include vomiting, diarrhea, difficulty breathing, and extreme drowsiness. In severe cases, an overdose can even lead to death. Treatment options for an overdose include pumping the stomach, administering an antidote, and providing supportive care.

Oxycodone/APAP Overdose: An Introduction

Oxycodone/APAP (Endocet®, Magnacet™, Percocet®, Roxicet™, Tylox®) is a prescription pain medication. As with any medication, it is possible to take too much, and an overdose can be lethal. The specific effects of an oxycodone/APAP overdose can vary, depending on a number of factors, including the dosage and whether it was taken with any other medications or substances.
 

What Are the Symptoms?

Both active ingredients in oxycodone/APAP can cause dangerous and life-threatening overdose symptoms. An overdose of the acetaminophen component of oxycodone/APAP may cause the following symptoms:
 
  • Irritability
  • Nausea
  • Vomiting
  • Diarrhea
  • Loss of appetite
  • Sweating
  • Yellowing of the whites of the eyes and skin (jaundice)
  • Dark urine
  • Confusion
  • Low blood sugar (hypoglycemia)
  • Bleeding
  • Liver failure
  • Loss of life.
     
An overdose of the oxycodone component of oxycodone/APAP may cause the following symptoms:
 
  • Difficulty breathing
  • Extreme drowsiness, leading to a coma
  • Cold, clammy skin
  • A slow heart rate (bradycardia)
  • Low blood pressure (hypotension)
  • Cardiac arrest
  • Loss of life.
     
 
Alternative Therapies for Pain Management

Oxycodone APAP Drug Information

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