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Oxycodone/APAP and Breastfeeding

Taking oxycodone/APAP and breastfeeding at the same time may not be a safe combination, as this medication does pass through breast milk. Although the APAP (acetaminophen) component is considered fairly safe to use while breastfeeding, the oxycodone component may cause significant problems in a nursing child. As a narcotic, oxycodone may cause side effects or could lead to dependence in the breastfed infant.

Is Oxycodone/APAP Safe While Breastfeeding?

Oxycodone/APAP (Endocet®, Magnacet™, Percocet®, Roxicet™, Tylox®) contains two different active ingredients. Both of these ingredients do pass through breast milk. If you are breastfeeding or are thinking about starting, talk with your healthcare provider before taking oxycodone/APAP.

Oxycodone/APAP and Breastfeeding: What Does the Research Say?

Although the acetaminophen (Tylenol®) component of oxycodone/APAP passes through breast milk, it is considered fairly safe (see Tylenol and Breastfeeding). However, the oxycodone component is a narcotic and may cause significant problems in a nursing infant. In addition to the possibility of side effects, the narcotic component could lead to dependence in the breastfed child.
Oxycodone/APAP is often used to treat pain after delivering a baby, and many healthcare providers are comfortable recommending the medication for this use. It is a good idea to watch for any problems, such as breathing problems, excessive sleeping, or feeding problems, if you take oxycodone/APAP while breastfeeding.

Discussing Oxycodone/APAP and Breastfeeding With Your Healthcare Provider

You should talk with your healthcare provider about oxycodone/APAP and breastfeeding. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision about oxycodone/APAP and breastfeeding that is right for you.
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