Pain Channel
Topics & Medications
Quicklinks
Related Channels

Drug Interactions With Oxycodone/APAP

Antipsychotic Medications
Combining an antipsychotic medication with oxycodone/APAP can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking these medications together.
 
Barbiturates
Taking a barbiturate with oxycodone/APAP can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking these medications together.
 
Benzodiazepines
Combining oxycodone/APAP in combination with a benzodiazepine might increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking these medications together.
 
Lamotrigine (Lamictal)
Oxycodone/APAP may decrease the level of lamotrigine in your blood, perhaps making it less effective. Check with your healthcare provider before combining these medications.
 
Other Acetaminophen Products
When taking oxycodone/APAP, you should limit your total daily dose of acetaminophen (from all sources combined) to no more than 4 grams (4000 mg) per day. The acetaminophen content of oxycodone/APAP varies, depending on the strength (the larger number -- for instance, 500 mg -- is the acetaminophen content). Taking too much acetaminophen could lead to serious liver damage or even death.
 
Watch for any other sources of acetaminophen, including other prescription pain relievers and many over-the-counter products, such as Tylenol. To be safe, all other acetaminophen products should be avoided while you are taking oxycodone/APAP, unless you are extremely careful to limit your total acetaminophen use (from all sources added together) to 4 grams per day.
Warning: 10 Hidden Sources of Lactose

Oxycodone APAP Drug Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.