The U.S. Food and Drug Administration (FDA) warns that people using NSAIDs other than aspirin, including oxaprozin, may be at higher risk for heart attack or stroke than those who do not take NSAIDs. This risk may be higher in people who have been taking them for a long time. These events can occur without any warning and can lead to death, so tell your healthcare provider if you have or ever had had any of the following:
- Heart disease or a heart attack
- High blood pressure (hypertension)
- High cholesterol.
You should also talk to your healthcare provider prior to taking oxaprozin if you have:
- Congestive heart failure
- Liver disease or liver failure
- Kidney disease or kidney failure
- Bleeding problems or are taking a medicine that decreases the blood's ability to clot
- Stomach ulcers, stomach bleeding, or a history of either condition
- Any allergies to medicines, including aspirin or other NSAIDs.
Let your healthcare provider know if you:
- Are pregnant or thinking about becoming pregnant (see Daypro and Pregnancy)
- Are breastfeeding
- Drink alcohol frequently
- Are having or have recently had heart surgery.
Also, tell your healthcare provider about all other medicines you are currently taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Oxaprozin to learn more, including information on who should not take the drug.)