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Opana ER Warnings and Precautions

People who have low blood pressure, certain lung problems, or other medical issues should review the risks that may apply to them if they take Opana ER. Other warnings and precautions apply to people using certain medications and women who are pregnant or breastfeeding. You should not take Opana ER if you have asthma or severe liver disease.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Opana® ER (oxymorphone ER) if you have:
  • Gallbladder or pancreatic disease
  • Narrowing of the digestive tract, often caused by:
    • Esophageal strictures
    • "Short gut" syndrome
    • Inflammatory bowel disease
    • Past history of peritonitis
    • Cystic fibrosis
    • Meckel's diverticulum
    • Past gastrointestinal surgery
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
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