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Opana ER

Abuse Potential

Opana ER contains oxymorphone, a drug that may be abused (see Opana ER Abuse). Make sure to keep this medication in a safe place, where it is unlikely to be stolen by others. Never let someone else take your medication, as it contains a high dose of oxymorphone that could easily result in death in someone who is not used to the medication.
 
Also, it is very dangerous to inject this medication, as it contains inactive ingredients that can be quite harmful when injected into the bloodstream. People who abuse Opana ER and suddenly stop using it are likely to experience withdrawal symptoms (see Opana ER Withdrawal).
 

When and How to Take It

Some general considerations to keep in mind during treatment with Opana ER include the following:
 
  • The medication comes as an extended-release tablet. It is taken by mouth twice a day (every 12 hours), every day. It is not meant to be taken "as needed" (at unscheduled times and only when needed for pain).
 
  • This medication absolutely must be taken on an empty stomach, at least one hour before or two hours after eating. Taking it with food leads to significantly high levels of the drug in the bloodstream, potentially leading to an overdose.
 
  • You must not consume alcohol or take any medications that contain alcohol, such as certain cough medications, while taking Opana ER. Alcohol can lead to extremely high levels of the drug in the bloodstream, potentially leading to an overdose.
 
  • Never crush, chew, or dissolve the tablets, as this would release a dangerous amount of oxymorphone. Never take a tablet that appears to be damaged in any way.
 
  • For the medication to work properly, it must be taken as prescribed. Do not increase your dose without your healthcare provider's approval. Do not suddenly stop taking Opana ER, especially if you have taken it regularly for more than a few days (see Opana ER Withdrawal).
 
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Opana ER Drug Information

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