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Opana ER Drug Interactions

Opana ER Interactions Explained

The following sections explain in detail the potentially negative reactions that can occur when Opana ER is combined with any of the drugs listed above.
 
Alcoholic Beverages
You must never consume alcohol, or even take medications that contain alcohol, while using Opana ER. Alcohol affects how the body handles Opana ER, and can lead to extremely high blood levels of the drug that may cause a fatal overdose.
 
Alvimopan
Opana ER may increase the risk of serious alvimopan side effects. Check with your healthcare provider before taking alvimopan if you have taken Opana ER in the past seven days.
 
Anticholinergics
Combining Opana ER with anticholinergic medications may increase the risk of constipation, intestinal blockage, or difficulty passing urine. Check with your healthcare provider before combining these medications.
 
Antidepressants
Combining an antidepressant with Opana ER could increase your risk for side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking Opana ER with an antidepressant, as you may need to be monitored more closely and the dose of your medications may need to be adjusted.
 
Antihistamines
Many antihistamines cause significant drowsiness and may lead to serious problems when combined with other medications that cause drowsiness, such as Opana ER. Check with your healthcare provider before taking Opana ER with an antihistamine, including nonprescription antihistamines.
 
Antipsychotics
Combining an antipsychotic medication with Opana ER can increase your risk for side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking Opana ER with an antipsychotic medication.
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Opana ER Drug Information

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