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Opana ER Dosage

General Information on Taking Opana ER

Some considerations to keep in mind during treatment with Opana ER include the following:
 
  • The medication comes as an extended-release tablet. It is taken by mouth twice a day (every 12 hours), every day. It is not meant to be taken "as needed" (at unscheduled times and only when needed for pain).
 
  • This medication absolutely must be taken on an empty stomach, at least one hour before or two hours after eating. Taking it with food leads to extremely high levels of the drug in the bloodstream, potentially leading to an overdose.
 
  • You must not consume alcohol or take any medications that contain alcohol, such as certain cough medications, while taking Opana ER. Alcohol can lead to extremely high levels of the drug in the bloodstream, potentially leading to an overdose.
 
  • Never crush, chew, or dissolve the tablets, as this would release a dangerous amount of oxymorphone. Never take a tablet that appears to be damaged in any way.
 
  • For the medication to work properly, it must be taken as prescribed. Do not increase your dosage without your healthcare provider's approval. Do not suddenly stop taking Opana ER, especially if you have taken it regularly for more than a few days (see Opana ER Withdrawal).
 
  • If you are unsure about anything related to your dosage or Opana ER dosing in general, please talk with your healthcare provider or pharmacist.
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