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Ofirmev Dosage

When treating pain or fever with Ofirmev, the dosage will depend on your age and weight, other medications you are taking, and other factors. Typically, for adults and adolescents who are at least 13 years old, the recommended dose is either 1000 mg every six hours or 650 mg every four hours. It is administered intravenously (by IV) over a period of about 15 minutes.

An Introduction to Dosing With Ofirmev

The dosage of Ofirmev™ (intravenous acetaminophen) your healthcare provider recommends will vary, depending on factors such as:
  • Your age
  • Your weight
  • Other medications you are taking
  • Other medical conditions you may have.

Ofirmev Dosage for Pain or Fever

For adults and adolescents (age 13 years old and older) who weigh at least 50 kg (110 pounds), the standard recommended Ofirmev dose is either 1000 mg every six hours or 650 mg every four hours. No matter what amount is used, the absolute maximum dosage for acetaminophen (from all sources, including oral medications) is 4000 mg per day.
For children under 13 years of age (and for adults and adolescents who weigh less than 110 pounds), the healthcare provider will calculate an appropriate dose based on weight.
The standard recommended intravenous (IV) dose for Ofirmev is the same as the oral dose of acetaminophen. This makes it easy, fast, and convenient to calculate the maximum dosage that can be given within 24 hours.
If you have kidney or liver disease, you may need a lower and/or less frequent dose of this medication.

General Information on Receiving Ofirmev

Some considerations for people receiving Ofirmev include the following:
  • This medication is given by IV every four to six hours.
  • Ofirmev may be given along with narcotic pain relievers.
  • Each dose should be given by IV drip over a period of about 15 minutes.
  • For the medication to work properly, it must be given as prescribed.
  • If you are unsure about anything related to your dosage, please talk with your healthcare provider or pharmacist.  
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Ofirmev Medication Information

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