Norco Drug Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Norco is combined with any of the drugs listed above.
Alcohol
It is usually recommended that you avoid alcohol while taking Norco. Alcohol interacts with the narcotic component of Norco (hydrocodone), potentially increasing the risk of serious side effects, such as extreme drowsiness, confusion, memory loss, or difficulty breathing. Alcohol also interacts with the
acetaminophen (
Tylenol®) component of Norco, increasing the risk of liver damage
(see Tylenol and Alcohol for more information).
Antidepressants
In some cases, combining an
antidepressant with Norco could increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking Norco with an antidepressant, as you may need to be monitored more closely and the dose of your medications may need to be adjusted.
Antihistamines
Many antihistamines cause significant drowsiness and can cause serious problems when used in combination with other medications that cause drowsiness, such as Norco. Check with your healthcare provider before taking Norco with an antihistamine, including non-prescription antihistamines.
Antipsychotic Medications
Combining an
antipsychotic medication with Norco can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking Norco with an antipsychotic medication.
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