There are numerous medicines that may cause drug interactions with Naprosyn, including other nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, cholestyramine, and ACE inhibitors. Among other things, Naprosyn drug interactions can cause your body to metabolize the medicines differently than intended and increase the risk of bleeding or developing stomach ulcers.
Corticosteroids, such as prednisone, hydrocortisone (Cortef®), dexamethasone (Decadron®, Dexone®, Hexadrol®), and many others.
Several herbal and nutritional supplements can also interact with Naprosyn and may increase the risk of bleeding. Examples of these include, but are not limited to: