Drug Interactions With Motrin: An Overview
Motrin® (
ibuprofen) has a number of medicines that it can potentially interact with. Some of these drug interactions with Motrin include:
- Warfarin (Coumadin®, Jantoven®)
- Other nonsteroidal anti-inflammatory drugs (NSAIDs), such as naproxen (Naprosyn®), naproxen sodium (Aleve®, Anaprox®, Naprelan®), diclofenac (Cataflam®, Voltaren®), indomethacin (Indocin®), nabumetone (Relafen®), oxaprozin (Daypro®), celecoxib (Celebrex®), meloxicam (Mobic®), etodolac (Lodine®), ketoprofen, ketorolac (Toradol®), and others
- Aspirin
- Lithium (Eskalith®, Lithane®, Lithonate®, Lithotabs®)
- Diuretics, such as torsemide (Demadex®), furosemide (Lasix®), and hydrochlorothiazide
- ACE inhibitors such as lisinopril (Zestril®, Prinivil®), fosinopril (Monopril®), catopril (Capoten®), quinapril (Accupril®), benazepril (Lotensin®), enalapril (Vasotec®), or ramipril (Altace®)
- Methotrexate (Rheumatrex®, Trexall™)
- Beta blockers, such as metoprolol (Lopressor®), propranolol (Inderal®), atenolol (Tenormin®), and metoprolol (Toprol XL®)
- Corticosteroids, such as prednisone, hydrocortisone (Cortef®), dexamethasone (Decadron®, Dexone®, Hexadrol®), and many others.
Several herbal and nutritional supplements can also interact with Motrin and may increase the risk of bleeding. Examples of these include, but are not limited to:
Warfarin (Coumadin, Jantoven)
If you are taking other blood thinners, such as warfarin, while taking Motrin, your body may metabolize them differently than intended. You healthcare provider may choose to monitor your INR and prothrombin time more frequently and adjust accordingly. INR and prothrombin time are tests used to measure how well you blood is clotting.
