Warnings and Precautions With Mefenamic Acid

To help ensure a safe treatment process, it is important to be aware of mefenamic acid precautions and warnings. For example, there are numerous potential side effects to be aware of, including congestive heart failure, kidney or liver damage, increased liver enzymes, and high blood pressure. Also, certain people should not take mefenamic acid, including those who are allergic to any components of the medicine.

Mefenamic Acid: What Should I Tell My Healthcare Provider?

Prior to taking mefenamic acid (Ponstel®), you should talk with your healthcare provider if you have:
 
  • Asthma
  • Heart disease, including congestive heart failure
  • High blood pressure (hypertension)
  • Liver disease or liver failure
  • Kidney disease or kidney failure
  • Bleeding problems or are taking medicines that decrease your blood's ability to clot
  • Diabetes
  • Nasal polyps
  • Systemic lupus erythematosus (lupus or SLE)
  • Stomach ulcers, stomach bleeding, or a history of either condition
  • Any allergies to medicines, including aspirin or other nonsteroidal anti-inflammatory (NSAID) pain medicines.
     
Let your healthcare provider know if you:
 
  • Are pregnant or thinking about becoming pregnant
  • Are breastfeeding
  • Drink alcohol frequently
  • Smoke
  • Are having or have recently had heart surgery.
     
Also, tell your healthcare provider about all other medicines you may currently be taking, including prescription and non-prescription medicines, antacids, vitamins, and herbal supplements.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
 
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