Mefenamic Acid

What Should I Tell My Healthcare Provider?

The U.S. Food and Drug Administration (FDA) warns that people using NSAIDs (other than aspirin), including mefenamic acid, may have a higher risk of having a heart attack or stroke than those who do not take NSAIDs. This risk may be higher in people who have been taking such medications for a long time. These events can occur without warning and can lead to death. Be sure to tell your doctor if you have or ever have had any of the following:
 
You should also talk with your healthcare provider prior to taking mefenamic acid if you have:
 
  • Asthma
  • Congestive heart failure
  • Liver disease or liver failure
  • Kidney disease or kidney failure
  • Bleeding problems or are taking a medicine that decreases your blood's ability to clot
  • Diabetes
  • Nasal polyps
  • Systemic lupus erythematosus (lupus or SLE)
  • Stomach ulcers, stomach bleeding, or a history of either condition
  • Any allergies to medicines, including sulfa drugs, aspirin, or other NSAID pain medicines.
     
In addition, let your healthcare provider know if you:
 
  • Are pregnant or thinking about becoming pregnant (see Ponstel and Pregnancy)
  • Are breastfeeding
  • Drink alcohol frequently
  • Smoke
  • Are having or have recently had heart surgery.
     
Also, tell your healthcare provider about all other medicines you may be taking, including prescription and nonprescription medicines, antacids, vitamins, and herbal supplements.
 
(Click Warnings and Precautions With Mefenamic Acid to learn more, including information on who should not take the drug.)
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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