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Drug Interactions With Mefenamic Acid

More Information on Interactions With Mefenamic Acid

The following sections explain in detail the potentially negative interactions that can occur if mefenamic acid is combined with any of the drugs listed above.
 
ACE Inhibitors
Mefenamic acid may decrease the blood pressure-lowering effects of ACE inhibitors. Your healthcare provider may need to adjust your doses of these drugs to prevent this interaction from occurring.
 
Angiotensin II Receptor Blockers (ARBs)
Mefenamic acid may affect an ARB's ability to lower blood pressure. Because of this interaction, your healthcare provider may need to adjust your doses of these drugs.
 
Antacids
Combining antacids and mefenamic acid may increase the amount of mefenamic acid in the blood. Taking antacids with mefenamic acid is generally not recommended.
 
Beta Blockers
Similar to other NSAIDs, mefenamic acid may decrease the blood pressure-lowering effects of beta blockers. Your healthcare provider may need to adjust your doses of these drugs to prevent this interaction from occurring.
 
Corticosteroids
Using corticosteroids with mefenamic acid can increase the risk for bleeding. Your healthcare provider may choose to monitor you more closely or adjust your doses of these drugs.
 
Cyclosporine
Taking mefenamic acid and cyclosporine together may increase your risk of kidney damage. Your healthcare provider may monitor you more closely and may need to adjust your doses of these drugs.
 
Diuretics
Mefenamic acid may reduce the activity of diuretics. Your healthcare provider may need to adjust your doses of these drugs to counteract this interaction.
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Mefenamic Acid Drug

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