Pain Home > Zipsor

Zipsor is a prescription pain medication that belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). It is approved to treat mild to moderate, short-term pain. The medicine comes in liquid-filled capsules and is taken by mouth, typically four times a day. Common side effects include headache, nausea, and vomiting.

What Is Zipsor?

Zipsor™ (diclofenac potassium) is a prescription medication approved for the treatment of mild to moderate acute (short-term) pain. It is the only diclofenac product available in liquid-filled capsules.
(Click Zipsor Uses for more information on what the medication is used for, including possible off-label uses.)

Who Makes Zipsor?

Zipsor is made by Xanodyne Pharmaceuticals, Inc.

How Does Zipsor Work?

Zipsor belongs to a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). Like other NSAIDs, it works by blocking a specific enzyme known as cyclooxygenase (COX), blocking the production of various inflammatory substances in the body.

When and How to Take It

Some general considerations include the following:
  • Zipsor comes in liquid-filled capsules and is usually taken by mouth four times a day.
  • It is usually recommended to take NSAIDs (like Zipsor) with food to help prevent stomach upset. However, food may cause this medication to work more slowly.
  • Try to space out your doses of this medication evenly throughout the day.
  • For the medication to work properly, it must be taken as prescribed.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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