Pain Home > Zipsor Drug Interactions
Zipsor may increase the level of digoxin in your bloodstream, increasing the risk of dangerous digoxin side effects. If you are taking digoxin, check with your healthcare provider before starting or stopping Zipsor.
Combining Zipsor with a diuretic can increase the risk of kidney problems, especially in people who already have kidney problems, and can decrease the effectiveness of the diuretic.
Taking Zipsor and lithium together may increase the levels of lithium in your body by reducing the kidneys' ability to remove lithium. Your healthcare provider may need to adjust your dose of these drugs and monitor the level of lithium in your blood.
"Blood Thinners" and Other Similar Drugs
Combining Zipsor with anticoagulants ("blood thinners"), antiplatelet drugs, or other medications that increase the risk of bleeding may lead to serious bleeding problems, including dangerous internal bleeding. Do not combine Zipsor with such medications without your healthcare provider's approval and supervision.
Zipsor may increase the risk of methotrexate toxicity. Do not combine these medications without your healthcare provider's supervision and approval.
Probenecid may increase the level of Zipsor in the blood, increasing the risk of side effects. Check with your healthcare provider before taking these medications together.
SSRIs or SNRIs