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Zipsor Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Zipsor is taken with any of the medications listed above.
ACE Inhibitors
Zipsor might reduce the effectiveness of ACE inhibitors for lowering blood pressure and may also increase the risk of kidney damage. If you take Zipsor with an ACE inhibitor, your healthcare provider should monitor your blood pressure to watch for this interaction.
Combining Zipsor with an ARB can increase the risk of kidney problems, especially in people who already have kidney problems, and can decrease the effectiveness of the ARB for lowering blood pressure.
Beta Blockers
Combining Zipsor with a beta blocker may interfere with the beta blocker's ability to lower blood pressure. Check with your healthcare provider before taking these medications together.
Bile Acid Sequestrants
Bile acid sequestrants can bind to Zipsor in the digestive tract and delay its absorption into the body. To avoid this drug interaction, Zipsor should be taken at least one hour before or four to six hours after the bile acid sequestrant has been taken.
Using corticosteroids with Zipsor can increase the risk of bleeding. Your healthcare provider may choose to monitor you more closely or adjust your dose of these drugs.
Zipsor may increase the level of cyclosporine in the blood, increasing the risk of serious cyclosporine side effects. In addition, this combination may increase the risk of kidney damage. Check with your healthcare provider before taking these medications together.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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