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Common Tramadol Side Effects

Tramadol has been studied thoroughly in clinical trials. In these studies, one group of people received the real medication, while another group was given a different pain medication. As a result, it is possible to see what side effects occurred, how often they appeared, and how they compared to the other medication.
 
In these studies, the most common side effects of tramadol included:
 
  • Constipation -- in up to 46 percent of people
  • Nausea -- up to 40 percent
  • Dizziness or a spinning sensation (vertigo) -- up to 33 percent
  • Headaches -- up to 32 percent
  • Drowsiness -- up to 25 percent
  • Vomiting -- up to 17 percent
  • Nervousness, shakiness, agitation, or other "overstimulation" problems -- up to 14 percent.
     
Other common side effects (occurring in 1 to 13 percent of people) included but were not limited to:
 
  • Itching
  • Weakness
  • Sweating
  • Indigestion or heartburn
  • Dry mouth
  • Diarrhea
  • Hot flashes or flushing
  • Confusion
  • Coordination problems
  • An unusual pleasant feeling (euphoria)
  • Small, pinpoint pupils
  • Sleeping problems
  • Abdominal pain (stomach pain)
  • Loss of appetite
  • Vision problems
  • Frequent urination or difficulty emptying the bladder fully
  • Menopause symptoms.
     
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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