Pain Home > Effects of Tramadol

Tramadol hydrochloride (Ultram®) is a prescription medication approved to treat moderate to moderately severe pain in adults (age 16 and older).
Tramadol is part of a group of medications called centrally acting opioid analgesics. This means that tramadol works in the central nervous system (the brain and spinal cord), acts much like morphine in the body, and relieves pain. It also works in a similar manner as some antidepressant medications by inhibiting the reuptake of certain brain chemicals (serotonin and norepinephrine).
The effects of tramadol can also cause psychological and physical dependence. Initially, this drug was marketed as a pain medication with little potential for abuse. However, healthcare providers quickly recognized that many of their patients had become addicted to tramadol. Now, the prescribing information for this medication contains numerous warnings about the potential for tramadol abuse.
(Click Tramadol for a more in-depth look at the effects of this drug, including information on how it works and how it can help relieve moderate to moderately severe pain in adults.)
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Last reviewed by: Kristi Monson, PharmD;
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