Pain Home > Sprix

If you have moderate to moderately severe pain, a healthcare provider may prescribe Sprix. This medication comes in the form of a nasal spray and is typically used every six to eight hours for up to five days. While most people tolerate this medicine well, side effects are possible and may include a runny nose, throat irritation, and nose pain.

What Is Sprix?

Sprix™ (ketorolac nasal spray) is a prescription medication approved to treat moderate to moderately severe pain for up to five days.
(Click Sprix Uses for more information, including possible off-label uses.)

Who Makes This Medication?

Sprix is manufactured by Roxro Pharma, Inc.

How Does Sprix Work?

Sprix belongs to a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). Like other NSAIDs, Sprix is thought to work by blocking the production of certain hormones that cause pain and inflammation in the body. These hormones are called prostaglandins. By blocking prostaglandins, Sprix helps to alleviate pain.

Clinical Effects of Sprix

Clinical studies have shown that Sprix can reduce pain from major surgery. In one study, people who were given Sprix experienced less intense pain in the two days after surgery, compared to those who received a placebo (a "sugar pill" that does not contain any active ingredients).
The people who were given Sprix also used 36 percent less morphine, a strong opioid pain medicine, than those who received the placebo pill.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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