If you have moderate to moderately severe pain, a healthcare provider may prescribe Sprix. This medication comes in the form of a nasal spray and is typically used every six to eight hours for up to five days. While most people tolerate this medicine well, side effects are possible and may include a runny nose, throat irritation, and nose pain.
What Is Sprix?
Sprix™ (ketorolac nasal spray) is a prescription medication approved to treat moderate to moderately severe pain for up to five days.
Sprix belongs to a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). Like other NSAIDs, Sprix is thought to work by blocking the production of certain hormones that cause pain and inflammation in the body. These hormones are called prostaglandins. By blocking prostaglandins, Sprix helps to alleviate pain.
Clinical Effects of Sprix
Clinical studies have shown that Sprix can reduce pain from major surgery. In one study, people who were given Sprix experienced less intense pain in the two days after surgery, compared to those who received a placebo (a "sugar pill" that does not contain any active ingredients).
The people who were given Sprix also used 36 percent less morphine, a strong opioid pain medicine, than those who received the placebo pill.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Sprix [package insert]. Menlo Park, CA: Roxro Pharma, Inc.;2009 October.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed January 24, 2013.
Lexi-Interact [computer program]. Lexi-Comp, Inc.; August 11, 2010.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed August 12, 2010.
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