Pain Home > Rybix ODT Drug Interactions

Rybix ODT Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Rybix ODT is combined with any of the drugs listed above.
You should avoid alcohol while taking Rybix ODT. Alcohol reacts with this medication, potentially increasing the risk of serious side effects, such as extreme drowsiness, confusion, memory loss, or difficulty breathing (see Tramadol and Alcohol for more information).
The combination of carbamazepine (a seizure medication) and Rybix ODT should be avoided. Carbamazepine decreases the level of Rybix ODT in the blood, making it less effective. In addition, tramadol increases the risk of seizures, especially in people with a seizure disorder (see Tramadol and Seizures).
Taking cyclobenzaprine with Rybix ODT increases the risk of seizures. This combination should be avoided if possible, especially in people who already have seizure problems.
Taking Rybix ODT with dextromethorphan can cause a group of symptoms called serotonin syndrome. These symptoms include:
  • Confusion
  • Hallucination
  • Fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasm
  • Difficulty walking
  • Diarrhea.
Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be dangerous (see Tramadol and Serotonin Syndrome for more information).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation

Topics & Medications


Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.